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A Study of Retatrutide (LY3437943) in Participants With Obesity or Overweight (NCT04881760)

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Meta-analyses of berberine studies suggest more modest effects, with HbA1c reductions of approximately 0.50.7% and variable weight loss, typically 13 kg over several months

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Last reviewed: May 20, 2026 Last updated: May 20, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

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Leptin, produced by fat cells, signals energy availability to the reproductive system

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Probiotics are sensitive to environmental conditions, and how you take them can influence whether the bacteria survive transit through the stomach and actually colonize the gut

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Some patients find that a quality probiotic helps stabilize their gut during the adjustment period

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